莫冬亮
点击数:16257 来源:维多利亚网站vic 作者: 录入:人员机构 更新时间:2018-12-27
莫冬亮 [教授]
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电子邮箱:moeastlight@163.com
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基本介绍
莫冬亮博士,广西师范大学教授,博士生导师。2006年毕业于南开大学化学系,2011年于中国科学院上海有机化学研究所获得有机化学博士学位,师从有机化学家戴立信院士和侯雪龙研究员。2011-2014年在美国University of Illinois at Chicago进行三年博士后研究。2014年9月以漓江学者引进至维多利亚网站vic。2014年11月入选广西高校引进海外高层次人才计划第二批。2015年12月破格晋升为教授并遴选为博士生导师,主要从事有机合成、金属有机化学及药物化学。以第一作者或通讯作者在Angew.Chem.Int.Ed.; Org.Lett.; Chem. Eur. J., J.Org.Chem. Organometallics, Synthesis等国际著名期刊发表SCI论文30余篇。目前主持国家自然科学基金3项(青年、地区、面上),广西自然科学基金2项,广西高层次人才计划基金1项,重点实验室主任基金1项。2016年获得广西杰出青年基金,并获得2016年德国Thieme Chemistry Journal Award,2017年广西高等学校“千名中青年骨干教师”第一期培育计划。
研究方向
学历背景
2011.8-2014.8 美国University of Illinois at Chicago,博士后(合作导师:Prof. Laura Anderson)
2006.9-2011.7中国科学院上海有机化学研究所,获博士学位(导师:戴立信 院士和侯雪龙 研究员)
2002.9-2006.7 南开大学化学系化学专业,获学士学位(导师:徐善生和王佰全 教授)
工作经历
2016.01 被遴选为广西师范大学博士生导师
2015.12 破格晋升为教授
2014.09 维多利亚网站vic,漓江学者,硕士生导师
社会任职
是国际著名有机化学期刊ACS Catalysis, Organic Letters, Adv. Synth. Catal., J. Org. Chem.; Eur. J. Org. Chem. Synthesis, ChemistrySelect等审稿人。
讲授课程
本科生《有机化学》、《有机合成》、《有机专论》、《化学专业英语》以及《有机化学基础实验2》。研究生的《有机合成》和《高等有机》。
论著专利
2014年11月成立课题组以来发表的SCI论文 (*为通讯作者, †为共同第一作者):
51. Cui Wei,Jie-Feng Zhu, Jin-Qi Zhang,Qi Deng,and Dong-Liang Mo*,Synthesis of Spirofluorenyl-beta-Lactams through Cycloaddition and Ring Contraction From N-Aryl Fluorenone Nitrones and Methylenecyclopropanes, Adv. Synth.Catal.2019, major revision.
50.Hong-Yan Bi†,Min Du†,Cheng-Xue Pan,* Yuhong Xiao, Gui-Fa Su,* and Dong-Liang Mo*, Nickel(II)-Catalyzed [5+1] Annulations of 2-Carbonyl-1-propargylindoles with Hydroxylamine to Synthesize Pyrazino[1,2-a]indole-2-Oxides in Water,J. Org.Chem. 2019, Major revision.
49. Hong-Ping Zhao, Xiao-Pan Ma, Shu-Min Nie, Yuhong Xiao, and Dong-Liang Mo*, Synthesis of Chromeno[4,3-b]quinolines and Spirobenzofuran-3,3'-quinolines through Silver-Mediated Appel Reaction/C-Br Bond Cleavage/Double Selective Rearrangement Sequence, Org. Chem. Front., 2019, 6, DOI: 10.1039/C9QO00417C.
48. Feng-Ping Liu†(2014级独秀班本科), Hong-Ping Zhao†,Shuang Tan, Xiuqiang Lu, Dong-Liang Mo*, Sodium Hydride Promoted C−C/C−O bond Cleavage to Prepare 2-(3-Methyleneindolin-2-yl)phenols, Synthesis, 2019, has been accepted.
47.Jing-Mei Yuan†, Kai Wei†, Guo-Hai Zhang, Nan-Ying Chen, Xin-Wei Wei,Cheng-Xue Pan*, Dong-Liang Mo*, Gui-Fa Su*,Cryptolepine and aromathecin based mimics as potent G-quadruplexbinding,DNA-cleavage and anticancer agents: Design, synthesis and DNA targeting-induced apoptosis,Eur. J. Med. Chem. 2019, 169, 144-158.
46. Qing-Qing Liu†,Ke Lu†,Hai-Miao Zhu, Shi-Lin Kong,Jing-Mei Yuan, Guo-Hai Zhang, Nan-Ying Chen, Chen-Xi Gu, Cheng-Xue Pan,* Dong-Liang Mo,* and Gui-Fa Su*,Identification of 3-(benzazol-2-yl)quinoxaline derivatives as potent anticancer compounds: Privileged structure-based design, synthesis, and bioactive evaluation in vitro and in vivo, Eur. J. Med. Chem. 2019, 165, 293-308.
45. Ning Zou†, Ji-Wen Jiao† (2015级独秀班本科生), Yu Feng, Cheng-Xue Pan, Cui Liang, Gui-Fa Su,* and Dong-Liang Mo*, Iron(III)/Copper(II)-Cocatalyzed Cycloaddition/[3,3]-Rearrangement /N−O Bond Cleavage to Prepare Polysubstituted Pyrrolizines from N-Vinyl-a,β-Unsaturated Nitrones and Activated Alkynes, Org. Lett. 2019, 21, 481-485.
44. Si-Yi Wu†(2014级独秀班本科生), Wei-Li Chen,† Xiao-Pan Ma, Cui Liang, Gui-Fa Su,* and Dong-Liang Mo*, Copper-Catalyzed [3+2] Cycloaddition and Interrupted Fischer Indolization to Prepare Polycyclic Furo[2,3-b]indolines from N-Aryl Isatin Nitrones and Methylenecyclopropanes, Adv. Synth. Catal. 2019, 361, 965-970.
43. Yan-Xiao Jiao, Lin-Su Wei, Chun-Yang Zhao, Kai Wei, Dong-Liang Mo,* Chen-Xue Pan,* and Gui-Fa Su*, Isobutyl Nitrite-Mediated Synthesis of Quinoxalines through Double C−H Bond Amination of N-Aryl Enamines, Adv. Synth. Catal.2018, 360, 4446-4451.
42. Xiao-Pan Ma, Liang-Gui Li, Hong-Ping Zhao, Min Du, Cui Liang, and Dong-Liang Mo*, Formal [7+2] Cycloaddition of Arynes with N-Vinyl-ɑ,β-Unsaturated Nitrones: Facile Synthesis of Benzoxazonines and Their N−O Bonds Cleavage, Org. Lett.2018, 20, 4571-4574 (IF =6.57, SCI一区).
41. Ji-Wen Jiao†(2015级独秀班本科), Hong-Yan Bi†, Pei-Sen Zou, Zhi-Xin Wang*, Cui Liang, and Dong-Liang Mo*, Copper-Mediated Difunctionalization of Alkenylboronic Acids: Synthesis of ɑ-Imino Ketones, Adv. Synth. Catal.2018, 360, 3254-3259 (IF = 5.64, SCI一区).
40. Wei-Li Chen,† Si-Yi Wu†(2014级独秀班本科), Xue-Ling Mo, Liu-Xu Wei, Cui Liang, and Dong-Liang Mo*, Synthesis of 2-Aminobenzonitriles through Nitrosation Reaction and Sequential Iron(III)-Catalyzed C−C Bond Cleavage of 2-Arylindoles, Org. Lett. 2018, 20, 3527-3530 (IF = 6.57, SCI一区)
39. Lin-Su Wei,† Guo-Xue He,† Xiang-Fei Kong, Cheng-Xue Pan*, Dong-Liang Mo*,and Gui-Fa Su*, Gold(III)-Catalyzed Selective Cyclization of Alkynyl Quinazolinone tethered Pyrroles: Synthesis of Fused Quinazolinone Scaffolds, J. Org. Chem., 2018, 83, 6719-6727. (IF = 4.84, SCI二区)
38. Chun-Hua Chen, Qing-Yan Wu (2016级独秀班本科), Cui Wei, Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*, Iron(III)-Catalyzed Selective N−O Bond Cleavage to Prepare Tetrasubstituted Pyridines and 3,5-Disubstituted Isoxazolines from N-Vinyl-ɑ,β-Unsaturated Ketonitrones, Green. Chem. 2018, 20, 2722-2729 (IF = 9.125, 被Green Chemistry选为封面, SCI一区).
37. Chun-Yang Zhao,† Kun Li† (2015级独秀班本科), Yu Pang, Jia-Qing Li, Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*, Iodine(III) Reagent-Mediated Intramolecular Amination of 2-Alkenylanilines to Prepare Indoles, Adv. Synth. Catal.2018, 360, 1919-1925 (IF = 5.64, SCI一区).
36. Hong-Yan Bi,† Feng-Ping Liu† (2014级独秀班本科), Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*, A Tunable Route to Prepare ɑ,β-Unsaturated Esters and ɑ,β-Unsaturated-γ-Keto Esters through Copper-Catalyzed Coupling of Alkenyl Boronic Acids with Phosphorus Ylides, Adv. Synth. Catal.2018, 360, 1510-1516 (IF = 5.64, SCI一区)
35. Xiang-Fei Kong, Feng Zhan, Guo-Xue He, Cheng-Xue Pan, Chen-Xi Gu, Ke Lu, Dong-Liang Mo*, and Gui-Fa Su*, Gold-Catalyzed Selective 6-exo-dig and 7-endo-dig Cyclizations of Alkynyl-Tethered Indoles to Prepare Rutaecarpine Derivatives, J. Org. Chem., 2018, 83, 2006-2017. (IF = 4.84, SCI二区)
34. Xiao-Hua Li† (2013级独秀班本科生), Ai-Hui Ye† (2014级化学班本科生), Cui Liang, and Dong-Liang Mo*, Substituent Effects of 2-Pyridones on Selective O-Arylation with Diaryliodonium Salts: Synthesis of 2-Aryloxypyridines under Metal-Free Conditions, Synthesis2018, 50, 1699-1710. (IF = 2.65, SCI三区).
33. Xue-Ling Mo†(2013级独秀班本科生), Chun-Hua Chen†, Cui Liang, and Dong-Liang Mo*, Copper-Catalyzed Carbonyl Group Controlled Coupling of Isatin Oximes with Arylboronic Acids to Prepare N-Aryl Oxindole Nitrones, Eur. J. Org. Chem.2018, 150-159. (IF= 2.83, 被主编选为特色封面,SCI三区).
32. Xiao-Pan Ma, Kun Li (2015级独秀班本科生), Si-Yi Wu, Cui Liang, Gui-Fa Su*, and Dong-Liang Mo*, Construction of 2,3-Quaternary Fused Indolines from Alkynyl tethered Oximes and Diaryliodonium Salts through A Cascade Strategy of N-Arylation/Cycloaddition/[3,3]-Rearrangement, Green Chemistry, 2017, 19, 5761-5766. (IF = 9.125, 被Green Chemistry选为封面和2017年度的Hot Article之一,, SCI一区).
31. Wei-Min Shi,† Xiao-Hua Li† (2013级独秀班本科生), Cui Liang, and Dong-Liang Mo*, Base-Free Selective O-Arylation and Sequential [3,3]-Rearrangement of Amidoximes with Diaryliodonium Salts: Synthesis of 2-Substituted Benzoxazoles, Adv. Synth. Catal.2017, 359,4129-4135. (IF = 5.64, SCI一区).
30. Ning Zou, Ji-Wen Jiao (2015级独秀班本科生), Yu Feng (2015级制药工程本科生), Chun-Hua Chen, Cui Liang, Gui-Fa Su,*, and Dong-Liang Mo*, Diastereoselective Synthesis of Nine-Membered Heterocycles via the Cycloaddition and Sequential Rearrangement of N-Vinyl Nitrones with Isocyanates, Adv. Synth. Catal.2017, 359, 3545-3550. (IF = 5.64, SCI一区).
29. Dong-Liang Mo*.
28. Dong-Liang Mo
27. Dong-Liang Mo
26. Dong-Liang Mo*,
25. Dong-Liang Mo*, Synthesis of N-Aryl Oxindole Nitrones through Metal-Free Selective N-Arylation Process, J. Org. Chem., 2017, 82, 3232-3238. (IF = 4.84, SCI二区)
24. Dong-Liang Mo*, Cycloaddition of Fluorenone N-Aryl Nitrones with Methylenecyclopropanes and Sequential [1,3]-Rearrangement: An Entry to Synthesis of Spirofluoenylpiperidin-4-ones, J. Org. Chem.2017, 82, 502-511.(IF = 4.84, SCI二区)
23. Dong-Liang Mo , Recent Advances in Arylation and Alkenylation of N-O bonds, Synthesis 2017, 49, 933-959. (IF = 2.65, SCI三区)
22. Dong-Liang Mo
21. Dong-Liang Mo*.
20. Dong-Liang Mo*. Transition Metal-Free Synthesis of Thiocyanato- or Nitro-arenes through Diaryliodonium Salts, Synthetic Communications 2016, 46, 963-970.(IF = 1.0, SCI四区)
19. Wei-Min Shi, Xiao-Pan Ma, Gui-Fa Su* and Dong-Liang Mo* “New developments of ketonitrones in organic synthesis” Organic Chemistry Frontiers 2016, 3, 116-130. (IF = 4.68, SCI二区)
18. Wei-Min Shi, Xiao-Pan Ma, Cheng-Xue Pan, Gui-Fa Su* and Dong-Liang Mo* “Tandem C−O and C−N bonds Formation Through O-Arylation and [3,3]-Rearrangement by Diaryliodonium Salts: Synthesis of N-Aryl Benzo[1,2,3]triazin-4(1H)-one Derivatives” J. Org. Chem. 2015, 80 (21), 11175-11183 (IF = 4.72, SCI二区)
17. Xiao-Pan Ma, Wei-Min Shi, Xue-Ling Mo (2013级独秀班本科生), Xiao-Hua Li (2013级独秀班本科生), Liang-Gui Li (2013级独秀班本科生), Cheng-Xue Pan, Bo Chen*, Gui-Fa Su* and Dong-Liang Mo* “Synthesis of α,β-Unsaturated N-Aryl Ketonitrones from Oximes and Diaryliodonium Salts: Observation of A Metal Free N-Arylation Process” J. Org. Chem. 2015, 80(20), 10098-10107 (IF = 4.72, SCI二区)
16. Qing-Rong Liu, Cheng-Xue Pan, Xiao-Pan Ma, Dong-Liang Mo* and Gui-Fa Su*. “(Diacetoxyiodo)Benzene (DIB) -Mediated Reaction of Ethynylcarbinols: An Entry to α,α’-Diacetoxy Ketones and Glycerol Derivatives” J. Org. Chem. 2015, 80 (12), 6496-6501 (IF = 4.72, SCI二区)
已授权的中国发明专利
1)莫冬亮,石维敏,马小盼,闭红艳,苏桂发,陈春华,邹宁。N-烯基苯并三唑类氮氧衍生物及其制备方法和应用。发文日:2018.09.21;申请国别:中国;专利号:201610317256.4
2)莫冬亮,石维敏,马小盼,闭红艳,苏桂发,陈春华,邹宁。N-芳基苯并三唑类氮氧衍生物及其合成方法。发文日:2018.09.21;申请国别:中国;专利号:201610315960.6
3)莫冬亮,邹宁,陈春华,冯钰,苏桂发。1-氧-2,8-二氮杂环壬烷衍生物及其合成方法。申请时间:2016.09.18;申请国别:中国;申请号:201610826407.9
4)莫冬亮,陈春华,马小盼,刘凤萍,潘毓敏,苏桂发。2,3-吲哚二酮-3-N-烯基硝酮衍生物及其合成方法和应用。申请时间:2016.09.26;申请国别:中国;申请号:201610851288.2
5)莫冬亮, 马小盼,吴思仪,陈威利,苏桂发。2,3-稠环吲哚啉衍生物及其合成方法和应用。申请时间:2017.06.29;申请国别:中国;申请号:201710518658.5
获奖情况
2017.12 入选广西高等学校“千名中青年骨干教师培育计划”第一期培育计划
2017.05 获得广西师范大学第十一届“十佳青年”称号
2016.10 获得广西自然科学基金杰出青年基金资助
2015.12 荣获2016年度德国Thieme Chemistry Journals Award期刊奖 (2016年全球约有70名有机合成领域青年学者入选)
2014.11 入选广西高校海外高层次人才
2014.09 广西师范大学漓江学者
其他
本课题组每年接收1名博士、2-3名研究生(接受第一志愿或调剂)及对科研感兴趣的本科生。
欢迎热爱有机化学的有志青年加入Mo group!!!